Blocking hippocampal STAT3 in those with alcohol use disorder may alleviate symptoms of depression associated with withdrawal.
Rat study reveals place cells in the hippocampus have the same patterns of activity whether they correctly, or incorrectly recall a memory. However, when the memory is incorrect, the activity begins later and is slower.
Mouse study reveals intermittent fasting improves long-term memory retention and promotes hippocampal neurogenesis. The findings could help to slow cognitive decline in older adults.
Decreased blood flow and blood oxygen levels to the hippocampus may explain symptoms of memory loss associated with Alzheimer’s. Researchers say increasing hippocampal blood flow could reverse or protect against symptoms of the neurodegenerative disorder.
Researchers have identified significant differences in gene activity between the anterior and posterior areas of the hippocampus. Genes associated with depression and other mood disorders are more active in the anterior hippocampus, while genes linked …
MicroRNA-132 regulates neurogenesis in the hippocampus, according to both mouse and human tissue studies. Restoring levels of microRNA-132 in mouse models of Alzheimer’s disease reduces neurogenetic deficits and restores cognitive abilities, researcher…
By three months, babies are already enlisting the hippocampus to help recognize and learn patterns, researchers report.
A new micro-grid recording device allowed researchers to measure hippocampal activity in epileptic patients. They found brain waves travel back and forth across the brain structure, integrating messages from different areas of the brain.
Researchers have uncovered the molecular structure of three major complexes of glutamate receptors in the hippocampus. The findings shed new light on the mechanisms behind memory and learning in the brain.
Phase precession plays a critical role in the human brain. Not only does it link sequential positions, but it also plays a role in abstract progression to a specific goal.
Novel gene therapy treatment prevents learning impairments and memory loss in mouse models of Alzheimer’s disease.
A new study sheds light on how highly sensitive people process information. After experiencing something emotionally evocative, brain activity displayed a depth of processing while at rest. Depth of processing is a key feature of high emotional sensiti…
Study reveals hippocampal maps predict context-dependent behaviors.
A neuroimaging study of people with Down syndrome reveals subtle differences in the structure and function of the hippocampus.
PsychLight, a newly developed genetically encoded fluorescent sensor, helped researchers identify a psychedelic compound that acts on beneficial neural pathways to treat psychiatric disorders without the hallucinogenic effect.
The SERPINA5 was strongly correlated with tau tangle progression in the hippocampus and cortex.
Spending time performing household chores may help to improve brain health, especially for older adults. Researchers found older adults who spent more time engaging in housework had greater brain volume, specifically in the frontal lobe and hippocampus…
Consuming high levels of sugar-sweetened beverages early in life may lead to memory problems during adulthood. Researchers found, compared to rats who consumed only water, those who drank sugar-sweetened beverages had difficulties in memory recall asso…
Within months of learning a new language, increased activity in brain areas associated with auditory processing, memory, and grammatical comprehension occurs. As language skills improve, the activity decreases.
A new genetic engineering strategy significantly reduces levels of tau in animal models of Alzheimer’s disease. The treatment, which involves a single injection, appears to have long-last effects.